O'Brien was born in Brookline, Massachusetts. He landed his first comedy job as a writer for the sketch comedy series Not Necessarily the News, after first serving as president of the Harvard Lampoon while attending Harvard University. After graduating, he moved to Los Angeles, where he wrote for several comedy shows. Following a move to New York City, he worked on the writing staff of Saturday Night Live and The Simpsons. O'Brien went on to serve as host of Late Night with Conan O'Brien from 1993 to 2009 and later The Tonight Show with Conan O'Brien. He is the only personality to ever serve as host for both the NBC Late Night and Tonight Show franchises. Conan is currently the host of Conan, a late-night talk show that airs on the American cable television station TBS.